NEHA MITTAL
Concord,NC
Summary
Senior Bioinformatics Scientist with 8+ years of post-graduate experience architecting production-grade NGS pipelines (WGS, Amplicon, Hybrid-capture) for clinical diagnostics and precision oncology. Expert in Nextflow, Python, and AWS cloud-native genomic systems. Proven leader in ISO 13485 and CAP/CLIA regulated environments, specializing in automated assay design, high-sensitivity variant detection (MRD), and leveraging AI Agents/LLMs to optimize software development lifecycles.
Overview
6
6
years of professional experience
1
1
Certification
Work History
Bioinformatics Lead (Functional) / Data Scientist
Bio-Rad Laboratories
Ann Arbor, MI
12.2022 - Current
- Technical Leadership: Lead bioinformatics delivery for PCROne assay design and exclusivity pipelines, coordinating cross-functional sprints across biochemistry, engineering, and QA/RA teams.
- Pipeline Architecture: Design and validate production-ready NGS pipelines using Nextflow and AWS, reducing turnaround time by 40% for large-scale clinical genomic datasets.
- AI Optimization: Leverage AI agents and LLMs (GitHub Copilot/GPT-4) to automate unit testing and refactor legacy bioinformatics code, increasing software development velocity by 25%.
- Regulatory Compliance: Author bioinformatics V&V (Verification & Validation) plans and design documentation in alignment with ISO 13485 and CAP/CLIA standards for clinical product release.
- Data Strategy: Architected a metadata-driven SQL database for curated genomic assets, supporting global R&D teams in target discovery and automated primer/probe design.
Post-Doctoral Fellow / Research Scientist
University of North Carolina at Charlotte
Charlotte, NC
01.2020 - 01.2022
- Architected a scalable spatial decision support system for surveillance, integrating NGS data with public health metrics.
- Developed ML models for risk classification and automated pathogen variant calling using Python and R.
- Mentored 5+ PhD and Master's students in bioinformatics pipeline development and statistical analysis.
Education
PhD - Biological Sciences (Genomic Data Science Focus)
University of North Carolina At Charlotte
Charlotte07.2020
Ph.D. - Forestry (Applied Genomics)
Forest Research Institute
Dehradun05.2011
Master of Science - Bioinformatics
University of North Carolina At Charlotte
Charlotte05.2018
Skills
- Bioinformatics: Nextflow (DSL2), WGS/WTS, Amplicon/Hybrid-capture, Variant Calling (Somatic/Germline), MRD, Metagenomics
- Data Science & AI: Python, R, Machine Learning, LLMs (GPT-4), AI Agents for Code Optimization, AlphaFold2, RFdiffusion
- Cloud & DevOps: AWS (Batch, S3, EC2, Lambda), Linux/Bash, Docker, Singularity, Git (CI/CD), SQL (PostgreSQL), Jira (Agile)
- Regulatory: ISO 13485, CAP/CLIA, NYS compliance, V&V Planning, Design Control, Clinical Data Standards
Certification
- Citations: 1010+; h-index: 10. Author of 18+ research articles in high-impact journals.
- Certifications: Data Science Architecture (IntelliPaat), Machine Learning (Soft Train).
Languages
English
Full Professional
Hindi
Native or Bilingual
Timeline
Bioinformatics Lead (Functional) / Data Scientist
Bio-Rad Laboratories
12.2022 - Current
Post-Doctoral Fellow / Research Scientist
University of North Carolina at Charlotte
01.2020 - 01.2022
PhD - Biological Sciences (Genomic Data Science Focus)
University of North Carolina At Charlotte
Ph.D. - Forestry (Applied Genomics)
Forest Research Institute
Master of Science - Bioinformatics
University of North Carolina At Charlotte